Conceptual developments in membrane transport, 1924-1974.

Conceptual developments in photosynthesis, 1924-1974.

Conceptual developments in metabolic control, 1924-1974.

A brief sketch is given of the development of the understanding of the respiratory mechanism in plants over the past 50 years. Against this background the following aspects of control are discussed: (a) nonreversibility of catabolic sequences; (b) compartmentation of reactions and reactants; (c) control by amount of enzyme; (d) control by NAD and NADP; (e) control by ADP supply; (f) pacemaker r...

Investigation of the Accompaniment of Calcium During Active Calcium Transport from Human Erythrocyte Ghosts

To determine whether a cell metabolite was involved in active calcium transport, the cell contents of human erythrocytes were subjected to high dilutions and the resultant ghosts were checked for their ability to actively transport calcium. It was found that the diluted erythrocyte ghosts did retain their capacity to actively transport calcium and that the characteristics of this transport proc...

Active transport of proline in membrane preparations from Mycobacterium phlei.

Active transport of proline was observed in both electron transport particles and cell membrane ghosts from Mycobacterium phlei. The transport of proline was dependent upon substrate oxidation and the presence of Li+ or Na+, but not upon the formation of a high energy phosphorylated intermediate. The requirement for Na+ was different from Na+ coupled transport systems which have been described;...

Long distance transport.

A few years ago, I attended a 1-day symposium on long distance transport at a national meeting in a country abroad. Towards the end of the day, as the participants became tired and no general agreement was in sight, one observer from an allied discipline remarked, "Why can't you translocation workers make any progress, you still discuss the same miserable old models that were proposed 40 years ...